Genotyping by Sequencing

Overview
 Genotyping-by-sequencing(GBS)은 차세대 염기서열분석(NGS)의 새로운 응용 기술로서, Genome complexity reduction을 이용하여 유전체상의 새로운 변이 정보를 발견 및 분석하는 기술입니다. 제한효소로 유전체를 절단하여 reduced representation DNA library를 구축하기 때문에 비용 효율이 매우 높으며, 대량 샘플의 개체변이 연구나 다수의 분자 마커 개발 등에 적합한 기술이라 할 수 있습니다.